MouSensor, Inc. is an early-stage biotech company that engineers super sniffer mice to build a live nose-on-a-chip. We have the bold vision to detect, discover and digitize every single smell on this planet; from the fragrances in a perfumer’s palette to odors associated with diseases such as Parkinson’s disease. It is our mission to unlock the power of a new field, Odoromics, and to establish the first-ever digital database of smell.
The MouSensor platform is the product of more than 25 years of fundamental research on the molecular biology of the sense of smell. The science behind the technology has been extensively validated by the co-founders of the company, Dr. Paul Feinstein and Dr. Charlotte D’Hulst, at Hunter College, CUNY in the heart of New York City. The MouSensor technology is published in the peer-reviewed journal Cell Reports in 2016.
Founded and headquartered in New York City, MouSensor, Inc. is honored to be part of a vibrant biotech entrepreneurial ecosystem which allows us to attract talented graduates and experts to achieve our scientific & commercial goals. MouSensor, Inc. is a certified NYC Innovation Hotspot, a member of the STARTUP NY program, a resident of the Downstate Biotechnology Incubator and a proud member of the Alexandria LaunchLabs® community. The Company has a Belgian subsidiary, MouSensor Europe BVBA.
Volatile odors in our environment bind specific sensors in the nose, called odorant receptors (ORs). Even though the full OR repertoire was identified in 1991, only 10% of all human ORs have a known ligand. The fundamental reason why large-scale odor-profiling of ORs has been lagging, is that ORs are notoriously hard to express outside their native environment (i.e., in vitro). Hence, conventional pharmacological screening methods cannot be used to identify which odors bind with what receptors. MouSensor, Inc. uses mice (our so-called MouSensors) as bioreactors to express large amounts of fully functional human ORs in their native environment, i.e., an olfactory sensory neuron (OSN). Our revolutionary platform technology allows us to easily customize different MouSensor lines and to build an entire library of animals covering the full human OR repertoire. We are now translating our in vivo technology to an ex vivo odor screening platform to build the first-ever human-nose-on-a-chip. To integrate the MouSensor biology with state-of-the-art nanochip technology, we have partnered with imec (Belgium), the world-leading R&D and innovation hub in nanoelectronics and digital technologies.