MouSensor, LLC

About us

 

Vision

MouSensor, LLC is an early stage biotech start-up that engineers super sniffer mice to build a human-nose-on-a-chip. We have the bold vision to detect, discover and digitize every single smell on this planet; from the fragrances in a perfumer’s palette to the Chardonnay in your wine cellar. We aim to establish a digital database of scents, much like the objective RGB code for vision, and to demystify the last mystery of the senses, Olfaction.

Expertise

The MouSensor platform is the product of more than 25 years of fundamental research on the molecular biology of the sense of smell. The science behind the technology has been extensively validated by the co-founders of the company, Dr. Paul Feinstein and Dr. Charlotte D’Hulst, at Hunter College, CUNY in the heart of New York City and was published in the peer-reviewed journal Cell Reports in 2016.

Eco-System

Founded and headquartered in New York City, we are proud to be part of a vibrant biotech entrepreneurial ecosystem which allows us to attract talented graduates and experts to achieve our scientific goals. MouSensor, LLC is a certified NYC Innovation Hotspot and resides in the Downstate Biotechnology Incubator in Brooklyn, NY.

Technology

Volatile odors in our environment bind specific sensors in the nose, called odorant receptors (ORs). Even though the full OR repertoire was identified in 1991, only 10% of all human ORs have a known ligand. The fundamental reason why large-scale odor-profiling of ORs has been lagging, is that ORs are notoriously hard to express outside their native environment (i.e., in vitro). Hence, conventional pharmacological screening methods cannot be used to identify which odors bind with what receptors. MouSensor, LLC uses mice (our so-called MouSensors) as bioreactors to express large amounts of fully functional human ORs in their native environment, i.e., an olfactory sensory neuron (OSN).  Our revolutionary platform technology allows us to easily customize different MouSensor lines and to build an entire library of animals covering the full human OR repertoire.  We are currently translating our in vivo technology to an ex vivo odor detection platform to build a human-nose-on-a-chip, which integrates the MouSensor biology with state-of-the-art chip technology. Our biological nose-on-a chip has tremendous potential in Flavor and Fragrance R&D, explosive detection and even in disease diagnostics and biomarker discovery.

Meet our team

 
Charlotte D'Hulst, PhD

Charlotte D’Hulst, PhD

Co-Founder
Paul Feinstein, PhD

Paul Feinstein, PhD

Co-Founder

Board Of Advisors

 

 

Charles Greer, PhD
Charles Greer, PhD
Scientific Advisor

Robert Margolskee, PhD
Robert Margolskee, PhD
Scientific Advisor

Dr. Randall Reed
Dr. Randall Reed
Scientific Advisor

Richard Crockett, MDRichard Crockett, MD
Business Advisor

Charles SrebnikCharles Srebnik
Business Advisor

Steve Sun, PhDSteve Sun, PhD
Business Advisor

News

 
CEO, Charlotte D’Hulst, selected to represent MouSensor, LLC at the annual Women in Bio Plenary Event in San Diego, CA.

CEO, Charlotte D’Hulst, selected to represent MouSensor, LLC at…

CEO, Charlotte D’Hulst, selected to represent MouSensor, LLC at the annual Women in Bio Plenary Event in San Diego, CA.
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MouSensor, LLC Wins Its First NSF SBIR Phase I Grant

MouSensor, LLC Wins Its First NSF SBIR Phase I…

MouSensor, LLC won its first NSF SBIR phase I grant ($225,000).
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MouSensor, LLC Wins Outstanding Pitch Award At NewYorkBIO

MouSensor, LLC Wins Outstanding Pitch Award At NewYorkBIO

MouSensor, LLC won the Outstanding Pitch Award at the annual NewYorkBIO conference on May 11, 2017.
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MouSensor, LLC Wins Grant From Michael J. Fox Foundation

MouSensor, LLC Wins Grant From Michael J. Fox Foundation

MouSensor LLC won a grant from the Michael J. Fox Foundation for Parkinson’s Research.
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EisnerAmper

EisnerAmper

MouSensor, LLC’s co-founder Charlotte D’Hulst was recently featured in EisnerAmper’s 2016-2017 winter issue of Catalyst on women in biotech.
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MouSensor’s Story Picked Up By Belgian Newspaper De Tijd

MouSensor’s Story Picked Up By Belgian Newspaper De Tijd

MouSensor, LLC’s story was picked up by the prestigious Belgian newspaper De Tijd (PDF).
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MouSensor Technology Covered By Science Magazine

MouSensor Technology Covered By Science Magazine

The MouSensor technology was covered by Science Magazine.
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MouSensor’s Breakthrough Technology Published In Cell Reports

MouSensor’s Breakthrough Technology Published In Cell Reports

The paper entitled: “MouSensor: A Versatile Platform to Create Super Sniffer Mice for Studying Human Odor Coding” was published on July 7th, 2016, in Cell…
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ELabNYC 2016

ELabNYC 2016

MouSensor, LLC was selected to participate in the prestigious Entrepreneurship Lab program, ELabNYC 2016, which teaches business skills and networks its participants.
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NYCRIN I-Corps

NYCRIN I-Corps

MouSensor, LLC received the award for “Best Team” in the Fall Cohort of the NYCRIN I-Corps program.
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